Stigmasterol Attenuates Triple-negative Breast Cancer Stem Cell Properties by Inhibiting JAK3

作者：Ruijuan Zhou, Yuzhu Zhang, Leqin Xu, Yang Sun · 发表于：Journal of Cancer · 年份：2025 · DOI：10.7150/jca.94822 · 被引用次数：9 · 研究领域：Medicinal Plant Pharmacodynamics Research、Cytokine Signaling Pathways and Interactions、MicroRNA in disease regulation

This study is the first to demonstrate that Stigmasterol inhibited metastasis and stemness of BCSCs by downregulating JAK3, which might provide a new method for the clinical application of Stigmasterol in breast cancer.