BRD7 Inhibited Immune Escape in Nasopharyngeal Carcinoma via Inhibiting PD-L1 Expression

作者：Yilin Guo, Jiaxue Lu, Xiaoxu Li, Shiqi Yan, Jieyu Zhou, Ziying Tian, Ying Liu, Nan Li, Qing Zhou, Xiayu Li, Lei Shi, Su Jiang, Mengna Li, Xiao Zhou, Donghai Huang, Zhaoyang Zeng, Songqing Fan, Wei Xiong, Ming Zhou, Guiyuan Li, Wenling Zhang · 发表于：International Journal of Biological Sciences · 年份：2025 · DOI：10.7150/ijbs.103703 · 被引用次数：10 · 研究领域：Peptidase Inhibition and Analysis、Chromatin Remodeling and Cancer、Cancer Research and Treatments

experiments, the results showed that BRD7 could not only inhibit the growth of tumors, but also play a better anti-tumor effect when combined with PD-L1 antibody. These results provided further evidence that BRD7 inhibited immune escape of NPC through down-regulating PD-L1 expression.