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BAP31-ELAVL1-SPINK6 axis induces loss of cell polarity and promotes metastasis in hepatocellular carcinoma

作者:Xi-Yang Zhang, Jing Wang, Xiaohua Liang, Dongbo Jiang, Yuanjie Sun, Chenchen Hu, Feiming Hu, Yuanli He, Yubo Sun, Junqi Zhang, Jiaqi Ding, Sirui Cai, Yueyue Wang, Shuya Yang, Kun Yang · 发表于:International Journal of Biological Sciences · 年份:2025 · DOI:10.7150/ijbs.102566 · 被引用次数:7 · 研究领域:Endoplasmic Reticulum Stress and Disease、Ubiquitin and proteasome pathways、RNA modifications and cancer

experiments verified that BAP31-ELAVL1-SPINK6 axis induced cell polarity loss and promoted metastasis in HCC. Our study shed new light on the mechanism of cell polarity loss and metastasis in HCC.