Cost-utility of a new psychosocial goal-setting and manualised support intervention for independence in dementia (NIDUS-Family) versus goal setting and routine care: an economic evaluation embedded within a randomised controlled trial

作者：Abdinasir Isaaq, Claudia Cooper, Victoria Vickerstaff, Julie Barber, Kate Walters, Iain Lang, Penny Rapaport, Vasiliki Orgeta, Kenneth Rockwood, Laurie T. Butler, Kathryn Lord, Gill Livingston, Sube Banerjee, Jill Manthorpe, Helen C. Kales, Jessica Budgett, Rachael Hunter · 发表于：The Lancet Healthy Longevity · 年份：2025 · DOI：10.1016/j.lanhl.2024.100676 · 被引用次数：9 · 研究领域：Dementia and Cognitive Impairment Research、Mental Health and Patient Involvement、Geriatric Care and Nursing Homes

BACKGROUND: NIDUS-Family is a psychosocial and behavioural intervention comprising six to eight sessions, delivered by non-clinical facilitators, and tailored to goals set by dyads of people with dementia and their unpaid or family carers. The intervention has been shown to be effective for attainment of personalised client goals. The current study aimed to determine whether the intervention is cost-effective. METHODS: In this cost-utility and cost-effectiveness analysis within a two-armed, single-masked, multisite, superiority randomised controlled trial, we recruited 302 people with dementia living in their own homes and their family carers from National Health Service community settings and social and print media across England. Participants were randomly allocated (2:1) to the NIDUS-Family intervention group or control (goal setting and routine care) group. Randomisation was blocked and site-stratified, with allocation by a remote web-based system. We calculated the probability that NIDUS-Family is cost-effective for a client with dementia based on quality-adjusted life-years from a health and social care perspective and from a societal perspective (additionally including family carer time and out-of-pocket costs), at £20 000-30 000 decision thresholds for additional quality-adjusted life-years compared with usual care over 12 months. Analyses were done using the intention-to-treat population. This study is registered with ISRCTN, ISRCTN11425138, and is completed. FINDING...