Long-term fucoxanthin treatment prevents cognitive impairments and neuroinflammation via the inhibition of Nogo-A in APP/PS1 transgenic mice

作者：Yujie Jiang, Huiyue Chen, Jiayi Xu, Jingyang Le, Wenni Rong, Zengyu Zhu, Yuan Chen, Chenwei Hu, Jinhan Cai, Yirui Hong, Shangwei Huang, Meilin Zheng, Xinyu Zhang, Chenhui Zhou, Jinrong Zhang, Shan He, Xiaojun Yan, Wei Cui · 发表于：Food & Function · 年份：2025 · DOI：10.1039/d4fo05034g · 被引用次数：13 · 研究领域：Seaweed-derived Bioactive Compounds、Echinoderm biology and ecology

the inhibition of Nogo-A. These results not only elucidate an anti-neuroinflammatory mechanism of fucoxanthin, but also provide strong support for the development of fucoxanthin as a novel food ingredient or drug for the treatment of AD.