EZH2 suppresses IR-induced ferroptosis by forming a co-repressor complex with HIF-1α to inhibit ACSL4: Targeting EZH2 enhances radiosensitivity in KDM6A-deficient esophageal squamous carcinoma

作者：Guizhen Pan, Yeye Xia, Mengyu Hao, Jiahao Guan, Qianqian Zhu, Tianqi Zha, Lei Sheng, Zhenfeng Zhao, Huaguang Pan, Weiyang Fang, Xiaoyong Xu, Xiangcun Chen, Shuguang Zhou, Zhuting Tong · 发表于：Cell Death and Differentiation · 年份：2025 · DOI：10.1038/s41418-025-01451-5 · 被引用次数：13 · 研究领域：Epigenetics and DNA Methylation、Ferroptosis and cancer prognosis、RNA modifications and cancer