IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control

作者：Béatrice Bréart, Katherine Williams, Stellanie Krimm, Tiffany Wong, Brandon D. Kayser, Lifen Wang, Eric Cheng, Mayra Cruz Tleugabulova, Romain Bouziat, Tianshi Lu, Kobe Yuen, Natalie Firmino, Daniel D. Bravo, Juliette Roels, Atish Bhakta, Jack Bevers, Isabelle Lehoux, Alan Gutierrez, Yajun Chestnut, Joanna E. Klementowicz, Teresita L. Arenzana, Ilseyar Akhmetzyanova, Elizabeth Dixon, Min Chen, Kazi Tasneem, Rajbharan Yadav, Hartmut Koeppen, Soyoung Oh, Lélia Delamarre, Haochu Huang, Shion A. Lim, Gerald Nakamura, Jianyong Wang, Chan Gao, Racquel Corpuz, Sören Müller, Nathaniel R. West · 发表于：Nature · 年份：2025 · DOI：10.1038/s41586-024-08510-w · 被引用次数：48 · 研究领域：Cancer Immunotherapy and Biomarkers、CAR-T cell therapy research、Immunotherapy and Immune Responses