Radical 1,3-Hydrosulfonylation of Vinyldiazo Compounds with Sulfinyl Sulfones

作者：Tian Jing, Yuan‐Li Ding, Wanting Fu, Zixu Zhang, Zikun Wang · 发表于：Organic Letters · 年份：2025 · DOI：10.1021/acs.orglett.4c04652 · 被引用次数：10 · 研究领域：Sulfur-Based Synthesis Techniques、Radical Photochemical Reactions、Cyclopropane Reaction Mechanisms

Sulfinyl sulfones, as high-valence sulfurization reagents, are widely used to assemble sulfur sources on carbon skeletons, such as one-, two-, and four-carbon synthons, to access organosulfur compounds. However, their reaction with three-carbon synthons has remained a mystery until now. We report here a radical 1,3-hydrosulfonylation of vinyldiazo compounds with sulfinyl sulfones. This reaction not only represents the first example of the reaction of sulfinyl sulfones with three-carbon synthons but also opens up the application of vinyldiazo compounds in radical monofunctionalization.