The prognostic significance of malnutrition in older adult patients with acute ischemic stroke

作者：Tiantian Jiang, Xingyu Zhu, Yanwei Yin, Hongjin Liu, Guangyun Zhang · 发表于：Frontiers in Nutrition · 年份：2025 · DOI：10.3389/fnut.2025.1529754 · 被引用次数：14 · 研究领域：Nutrition and Health in Aging、Dysphagia Assessment and Management、Inflammatory Biomarkers in Disease Prognosis

Background Malnutrition is associated with an unfavorable prognosis; however, malnutrition in hospitalized patients is frequently overlooked by clinicians. This highlights the importance of accurately assessing nutritional status and providing appropriate nutritional supplementation. The most appropriate nutritional assessment tool for predicting the short-term prognosis of older adult patients with Acute Ischemic Stroke (AIS) was identified from five nutritional assessment tools, including the Prognostic Nutrition Index (PNI), the Hemoglobin, Albumin, Lymphocyte and Platelet (HALP) Score, the Naples Prognostic Score (NPS), the Geriatric Nutritional Risk Index (GNRI), and the Controlling Nutritional Status (CONUT) Score. Methods A total of 585 older adult patients with Acute Ischemic Stroke (AIS) were retrospectively analyzed and divided into two groups according to the modified Rankin Scale (mRS) score. The first group, comprising 111 cases, was classified as having a poor prognosis (mRS score > 2), while the second group, consisting of 391 cases, was classified as having a good prognosis (mRS score ≤ 2). A total of five nutritional assessment tools, including PNI, HALP Score, NPS, GNRI, and CONUT, were employed to evaluate the nutritional status of older adult patients with AIS and for the analysis of the relationship between nutritional status and prognosis. The incremental value of five nutritional assessment tools in predicting patient prognosis was compared by me...