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WTAP-Mediated N6-Methyladenosine Modification Promotes Gastric Cancer Progression by Regulating MAP2K6 Expression

作者:Han Shuangshuang, Haibin Jiang, Jia Wang, Chao Li, Ting Liu, Mingda Xuan, Bo Tian, Yi Si, Hongyan Zhao, Yunxia Zhao, Zhen-Long Zhu, Weifang Yu, Lihong Wang · 发表于:Journal of Cancer · 年份:2025 · DOI:10.7150/jca.98559 · 被引用次数:4 · 研究领域:RNA modifications and cancer、Autophagy in Disease and Therapy、Epigenetics and DNA Methylation

A modification promotes the proliferation, migration, and invasion of GC cells by positively regulating the target gene MAP2K6. This underscores the potential therapeutic significance of targeting the WTAP-MAP2K6 axis in combating GC occurrence and progression.