An endoplasmic reticulum-targeting hydroxyl radical fluorescent probe for imaging of ferroptosis and screening of natural protectants

作者：Hongyu Li, Xue Luo, Yue Jian, Jiajia Lv, Xinmin Li, Jie Gao, Wen Shi, Xiaohua Li, Zeli Yuan, Huimin Ma · 发表于：Chemical Science · 年份：2025 · DOI：10.1039/d4sc07953a · 被引用次数：21 · 研究领域：RNA modifications and cancer、Ferroptosis and cancer prognosis、interferon and immune responses

imaging of ˙OH in a mouse tumor model. This work provides not only a new tool for ferroptosis monitoring but also a direct insight into the regulation mechanism of ferroptosis and development of new drugs for ferroptosis-related diseases.