Mechanical properties, degradation action, and biocompatibility of in situ nanoparticle-reinforced MgxZny/Zn composite prepared via roll bonding

作者：Jianguo Lin, Yingzhong Chen, Yilong Dai, Xiaokai Zhang, Dechuang Zhang, Yuncang Li, Cuié Wen · 发表于：Acta Biomaterialia · 年份：2025 · DOI：10.1016/j.actbio.2025.01.048 · 被引用次数：47 · 研究领域：Magnesium Alloys: Properties and Applications、Aluminum Alloys Composites Properties、MXene and MAX Phase Materials

Zinc (Zn)-based alloys and composites are anticipated to emerge as a category of degradable metallic biomaterials with exceptional prospects for bone-implant applications owing to their superior biocompatibility and biofunctionality. Unfortunately, the limited strength of Zn alloys in their as-cast state restricts their use in clinical applications. In this study, we started with pure magnesium (Mg) powders and Zn sheets, and successfully fabricated Mg x Zn y /Zn composites using accumulative roll bonding (ARB). The influence of varying ARB cycle numbers on their microstructures, performance in relation to mechanical parameters, corrosion resistance, and cytotoxicity was comprehensively studied. Following 15 ARB cycles, the composites demonstrated a refined Zn matrix phase with grains of 0.3 μm and uniformly distributed in situ nanoparticle reinforcements of Mg 2 Zn 11 and MgZn 2 . The composites after 15 ARB cycles exhibited an ultimate tensile strength of 560 MPa, yield strength of 540 MPa, and elongation of 12 %, significantly better than the mechanical properties of most Zn alloys reported to date. The significant improvement in the composites’ strength is primarily attributable to refinement of grain size and dispersion strengthening, both of which are facilitated by the in situ incorporation of nanoparticles. The corrosion rate reduced with more ARB cycles and after 15 ARB cycles the composites had an electrochemical corrosion rate of 150.2 μm/y and an immersion degrada...