γ-Linolenic acid derived from Lactobacillus plantarum MM89 induces ferroptosis in colorectal cancer

作者：Yan Chen, Yijie Zhang, Mengmeng Dai, Cheng Qiu, Qinsheng Sun, Tingting Fan, Yuan Guo, Liqing Zhao, Yu‐Yang Jiang · 发表于：Food & Function · 年份：2025 · DOI：10.1039/d4fo04790g · 被引用次数：10 · 研究领域：Cholangiocarcinoma and Gallbladder Cancer Studies、Ferroptosis and cancer prognosis、Tannin, Tannase and Anticancer Activities

Lipid metabolism is crucial for cancer cell survival. γ-Linolenic acid derived from L. plantarum MM89 disrupts mitochondrial function to induce ferroptosis, thereby aiding tumor inhibition.