In vitro degradation, photo-activated antibacterial activity of sodium copper chlorophyllin crosslinked-polysilane composite coating on magnesium alloys

作者：Lan‐Yue Cui, Wei Wang, Zhen-Yu Zhang, Xuewen Jiang, Yukun Du, Bo Liu, Shuo‐Qi Li, Cheng‐Bao Liu, Yongming Xi, Rong‐Chang Zeng · 发表于：Corrosion Communications · 年份：2025 · DOI：10.1016/j.corcom.2024.07.003 · 被引用次数：13 · 研究领域：Nanoplatforms for cancer theranostics、Advanced Photocatalysis Techniques、Photodynamic Therapy Research Studies

• The PMTMS/SCC-MAO coating prevents the in-diffusion of Cu 2+ ions, avoiding galvanic corrosion. • MAO/PMTMS-SCC coating has a triple antimicrobial mechanism of Cu 2+ ions, PTT and PDT. • The PMTMS/SCC-MAO coating showed good cytocompatibility. Non-invasive inactivation of bacteria by photodynamic therapy (PDT) and photothermal therapy (PTT) has been recently concerned for biomaterials. A polymethyltrimethoxysilane (PMTMS)-crosslinked sodium copper chlorophyllin (SCC) coating was prepared on micro arc oxidation (MAO) coated magnesium alloy AZ31 by one-step dipping method. Results showed that the MAO/PMTMS-SCC coating had high corrosion resistance with two magnitudes decrease in corrosion current density. Profound physical barrier and sealing effects of PMTMS-SCC coating in the initial stage of immersion prevented in-diffusion of Cu 2+ , thus, primeval renegaded Cu was released to corrosive solution, instead of triggering galvanic corrosion. Antibacterial ratios under irradiation of 808 nm near infrared light against E. coli and S. aureus were 99.6% and 99.1%, respectively, which is ascribed to a triple antibacterial mechanism. Such a composite coating also displays high biocompatibility, which will promote the application of magnesium alloys in biomedical fields.