Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021

作者：Jing Chen, Zedong Li, Hong Liu · 发表于：Frontiers in Nutrition · 年份：2025 · DOI：10.3389/fnut.2024.1540485 · 被引用次数：6 · 研究领域：Child Nutrition and Water Access、Nutrition and Health in Aging、Global Public Health Policies and Epidemiology

Background: Nutrient deficiency disorders (NDs) harm growth, causing economic losses. Addressing NDs is a global priority, yet recent data is limited. This study examines latest NDs data across 204 countries and 21 regions from 1990 to 2021. Methods: Data from the 2021 Global Burden of Disease (GBD) study were used to analyze NDs-related incidence, prevalence, deaths, and disability-adjusted life years (DALYs) at global, national, and regional levels. Joinpoint regression analysis was applied to evaluate temporal trends, with Estimated Annual Percentage Change (EAPC) assessing long-term patterns. Results: In 2021, the global burden of NDs remained substantial, with a total of 1,845,246,558 cases with an ASPR of 23,858.99 cases per 100,000 individuals (95% UI: 23,445.77-24,320.82). The ASIR was 7,725.1 per 100,000 people (95% UI: 7,404.01-8,109.01), while the ASMR was 3.03 per 100,000 persons (95% UI: 2.69-3.4). Additionally, age-standardized DALYs rate was 657.62 per 100,000 individuals (95% UI: 489.93-869.58). Regionally, areas with low SDI exhibited the greatest ASPR, ASIR, ASDR, and age-standardized DALYs rates, whereas high SDI regions had the lowest rates. Conclusions: Although global NDs burden has declined from 1990 to 2021, regional and demographic disparities remain. Enhanced healthcare access in high-risk SDI regions is essential to further mitigate NDs's global impact.