Real–world outcomes on myopia management efficacy of diverse segmented defocus optics (DSDO) and defocus incorporated multiple segments (DIMS) spectacle lenses in Chinese children: An initial 12–month prospective clinical study

作者：Yuzhuo Fan, Huihui Chu, Zisu Peng, Jingwei Zhou, Jiahui Ma, Yuchang Lu, Chenxu Zhao, Yanyan Wang, Qiulin Deng, Jifeng Yu, Yan Li, Kai Wang, Mingwei Zhao · 发表于：Journal of Optometry · 年份：2025 · DOI：10.1016/j.optom.2024.100533 · 被引用次数：13 · 研究领域：Ophthalmology and Visual Impairment Studies、Retinal Diseases and Treatments、Ocular Surface and Contact Lens

PURPOSES: To investigate the 12-month effectiveness of Diverse Segmented Defocus Optics (DSDO) and Defocus Incorporated Multiple Segments (DIMS) spectacle lenses in a real-world clinical population in myopic and pre-myopic Chinese children. METHODS: About 364 subjects prescribed DSDO or DIMS were enrolled. Axial length (AL) and cycloplegic spherical equivalent refraction (SER) changes over 12 months were measured. The subjects were further divided into age sub-group (6-9; 10-14) and SER sub-group (+0.75D≤SER<-0.50D; -0.50D≤SER<-2.00D; -2.00D≤SER<-4.00D; SER≤-4.0D). Contrast sensitivity and visual experience were also reported. The rate of myopia progression was compared with historical single-vision spectacles (SVS) lenses data to evaluate the effectiveness of the regime. RESULTS: 317 subjects were analyzed. At 12-month, AL changes in the DSDO and DIMS group were 0.16±0.16 mm and 0.21±0.22 mm, respectively (P = 0.0202). DSDO spectacle lenses had better control effect in +0.75D≤SER<-0.50D and SER≤-2.0D sub-groups. The proportion of participants had no greater than 0.20 mm AL elongation was 65.00% and 55.41% of in DSDO and DIMS group separately. Myopia control effect in DSDO group was 47%-69% and 33%-62% in DIMS group compared to historical SVS lenses. CONCLUSIONS: Both DSDO and DIMS spectacle lenses retarded AL elongation. DSDO showed more stable myopia control effect comparing to DIMS, especially in groups of SER≤-2.0D sub-groups and older patients. DSDO showed initial potent...