Baseline characteristics of patients in the Chinese Bronchiectasis Registry (BE-China): a multicentre prospective cohort study

作者：Jin‐Fu Xu, Jin-Fu Xu, Hui-Zhen Zheng, Hai‐Wen Lu, Ling-Wei Wang, Bin Wu, Xiaodong Lv, Hong Luo, Jian Feng, Lin Liu, Lin Liu, Jinguang Jia, Weiqiang Mo, Hongyan Gu, Jingbo Jiang, Daoxin Wang, Bin Wang, Li Li, Yuan Zhi, Wen Li, Min Xie, Zhijun Jie, Xiaoyun Fan, Dan Li, Xinlun Tian, Min Zhang, Wei-Jie Guan, Hong Fan, Yuanlin Song, Jian He, De-Jie Chu, Chunling Du, Jianquan Zhang, Chao Cao, Jieming Qu, Jie-Ming Qu, James D Chalmers, Jin-Fu Xu, Jin-Fu Xu, Rong-Chang Chen, Ling-Wei Wang, Bin Wu, Xiao-Dong Lv, Jie-Ming Qu, Jie-Ming Qu, Hong Luo, Jian Feng, Yuan-Yuan Li, Lin Liu, Jin-Guang Jia, Wei-Qiang Mo, Hong-Yan Gu, Jing-Bo Jiang, Dao-Xin Wang, Bin Wang, Li Li, Zhi Yuan, Wen Li, Min Xie, Zhi-Jun Jie, Xiao-Yun Fan, Dan Li, Xinlun Tian, Min Zhang, Wei-Jie Guan, Hong Fan, Yuan-Lin Song, Jian He, De-Jie Chu, Chun-Ling Du, Jian-Quan Zhang, Chao Cao, Jing-Min Deng, Fan Li, Yu Chen, Gan-Zhu Feng, Xiao-Lin Chen, Yun-Hui Zhang, Jing-Qing Hang, Feng-Ying Zhang, Xiong-Biao Wang, Xu-Ming Luo, Liang Dong, Yu-Ping Li, Qing-Wei Meng, Tao Ren, Yan-Liang Ma, Qin Jia, Zhao Yang, Chang-Xi Zhang, Hao Tang, Peng-Fei Wang, Hong-Min Wang, Bei He, Ning Shen, Fei Xu, Yu Li, De-Dong Ma, Cui-Xia Zheng, Li-Min Wang, Ke-Jing Ying, Xiao-Qun Ye, Yang-Dan Zou, Jian-Ying Zhou, Ya-Hong Sun, Bing Li, Bi Chen, Jun Wang, Xin Yao, Bin Cao, Fen Hu, Xiao-Yan Jin, Jie Huang, Wei Jia, Zhong-Min Qiu, Chang-Ming Wang, Xian-Mei Zhou, Xin-Ling Gao, Jing Li, Xin Su, Zhen-Zhong Su, Yong Lin, Qiao Zhang, Xiao-Lian Song, Xi-Wen Gao, Jian-An Huang, Yi-Ming Zeng, Xia-Hui Ge, Wei-Ning Xiong, Wan-Li Ma, Xian-Ling Lu, Bi-Wen Mo, Miao Luo, Xue-Dong Liu, Hua Niu, Kai Wang, Wei Wang, Shao-Feng Zhan, Xiao-Ju Zhang, Qun Lv, Ying-Hua Guo, Wei Zhang, Xiang-Qi Chen, Min Zhang · 发表于：The Lancet Respiratory Medicine · 年份：2025 · DOI：10.1016/s2213-2600(24)00364-3 · 被引用次数：32 · 研究领域：Cystic Fibrosis Research Advances、Neonatal Respiratory Health Research、Chronic Obstructive Pulmonary Disease (COPD) Research

BACKGROUND: Bronchiectasis is a disease with a global impact, but most published data come from high-income countries. We aimed to describe the clinical characteristics of patients with bronchiectasis in China. METHODS: The Chinese Bronchiectasis Registry (BE-China) is a prospective, observational cohort enrolling patients from 111 hospitals in China. Data on demographics, comorbidities, and aetiological testing results were collected from adult patients with bronchiectasis at baseline and annual follow-up. Patients who met the inclusion criteria (age ≥18 years; received chest high-resolution CT in the past year showing bronchiectasis affecting one or more lung lobes; and clinical history consistent with bronchiectasis, including chronic cough, daily sputum production, and history of exacerbations) were included. Patients with known cystic fibrosis were excluded. To investigate variations according to different economic regions, two groups were compared based on whether per capita disposable income of residents was greater than US$5553. Clinical characteristics were compared with the European (EMBARC) registry and other national registries. FINDINGS: Between Jan 10, 2020, and March 31, 2024, 10 324 patients from 97 centres were included in the study. Among 9501 participants with available data, the most common cause of bronchiectasis was post-infective disease (4101 [43·2%] patients), followed by idiopathic (2809 [29·6%] patients). 6676 (70·0%) of 9541 patients with available...