Synergistic SERS effects in organic/MoS 2 heterojunctions with cavity structure enabling nanoplastics screening and antibiotic adsorption behavior detection

作者：Liqi Ma, Abdur Rahim, Boyao Lyu, Muhammad Saleem, Xiaoyu Zhang, Mingyue Li, Muhammad Noaman Zahid, Liwen Liu · 发表于：Chinese Physics B · 年份：2025 · DOI：10.1088/1674-1056/ada888 · 被引用次数：3 · 研究领域：Advanced biosensing and bioanalysis techniques、Microplastics and Plastic Pollution、Biosensors and Analytical Detection

Abstract The detection of nanoplastics (NPs) and their interactions with antibiotics is critical due to their potential environmental and health risks. Traditional detection methods are challenged by the small size and chemical similarity of NPs to microplastics. Current surface-enhanced Raman scattering (SERS) substrates for NP detection are limited by high cost, reliance on single enhancement modes, and insufficient sensitivity and selectivity, especially for NP-antibiotic complexes. In this study, the F/M-AAO substrate, which integrates 2,3,5,6-tetrafluoro-tetracyanoquinodimethane (F 4 TCNQ) and molybdenum disulfide (MoS 2 ) with anodic aluminum oxide (AAO) templates, is used to enhance the detection of NPs and NP-antibiotic complexes. The conical cavity structure of the substrate facilitates the enrichment and direct detection of NPs with diameters smaller than 450 nm. The three-dimensional (3D) F/M-AAO substrate achieved a limit of detection (LOD) of 1.73 × 10 6 ng/L for 100-nm NPs and a minimum detection concentration of 10 −10 M for ciprofloxacin adsorbed on NPs (NPs-CIP). It demonstrated remarkable sensitivity and selectivity in the detection of both individual NPs and NP-antibiotic complexes. This work highlights the innovative application of the F/M-AAO substrate in the SERS detection of NPs and NP-antibiotic complexes, providing a low-cost and effective platform for monitoring emerging environmental contaminants.