Brain near-infrared study of upstairs movement after anterior cruciate ligament reconstruction

作者：Ziyuan Cao, Hao Zhang, Xipeng Wu, Yuxuan Zhang, Jiangli Yu, Wei Li · 发表于：Frontiers in Neurology · 年份：2025 · DOI：10.3389/fneur.2024.1500579 · 被引用次数：5 · 研究领域：Optical Imaging and Spectroscopy Techniques、Laser Applications in Dentistry and Medicine、Spinal Cord Injury Research

Objective After anterior cruciate ligament reconstruction (ACLR), patients undergo specific changes in body and specific brain functions, which stem from neuroplasticity. In this study, we employed functional near-infrared spectroscopy (fNIRS) to investigate the characteristics of brain activation in patients after ACLR during a repetitive upstairs task, and compared them with healthy individuals. We aimed to provide a new theoretical basis for the changes in brain function after ACLR and neurorehabilitation of sports injuries. Methods A total of 27 patients who undergoing right ACLR and 27 healthy controls participated in the study. We utilized fNIRS to collect hemodynamic data from the frontal and parietal cortices of both groups during a repetitive upstairs task. The Lysholm scale assessment was conducted prior to the commencement of the task. Compare the functional characteristics of the brain in post-operative patients and healthy subjects during upstairs tasks, and examine the functional differences between the two groups. Results (1) Patients undergoing ACLR demonstrated a significant negative change in β -value for Channel 25 ( t = 4.0461, p = 0.0067) during the repetitive upstairs task. (2) In contrast, the healthy control group exhibited a significant increase in β -value across Channel 6 ( t = −3.0489, p = 0.0066), Channel 7 ( t = −4.5723, p = 0.0002), Channel 8 ( t = −3.0089, p = 0.0072), Channel 13 ( t = −2.8789, p = 0.0096), Channel 20 ( t = −3.4200, p = 0.0029)...