Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study

作者：Esat Kivanc Kaya, Burçin Halaçlı, Göksel Güven, Mehmet Erol Yildirim, Asir Eren Seven, Emin Gemcioğlu, Meltem Şimşek, Begum Erdemir Sullu, Recep Civan Yüksel, Ahmet Safa Kaynar, Aliye Esmaoğlu, Banu Kılıçaslan, Seda Banu Akıncı, Kürşat Gündoğan, Ebru Ortaç Ersoy, Jordi Rello, Arzu Topeli̇, On behalf of the Turkish Intensive Care Studies-Network (TRICS-Net) · 发表于：BMC Infectious Diseases · 年份：2025 · DOI：10.1186/s12879-024-10416-x · 被引用次数：5 · 研究领域：Disaster Response and Management、Earthquake Detection and Analysis、earthquake and tectonic studies

BACKGROUND: Scarce evidence is available on the epidemiology of microbiologically proven clinical infections in patients admitted to the intensive care unit (ICU) after a great earthquake. The main aim of this study was to assess clinical infections and microbiological features in patients admitted to the ICU following the 2023 earthquake in the southeastern region of Türkiye with a focus on the timing of culture positivity during their ICU stay. The secondary objectives included determining antibiotic susceptibility patterns, identifying the types of antibiotics administered upon ICU admission, evaluating the appropriateness of antibiotic usage, assessing patient outcomes, and identifying factors that influence microbiologically confirmed clinical infections. METHODS: A retrospective, multicenter, observational study was conducted on adult earthquake victims admitted to the ICU after the 2023 earthquake in southeastern Türkiye. Patients were categorized into four groups on the basis of culture positivity timing at the 72-hour breakpoint and clinical characteristics were compared among these groups. Factors influencing microbiologically proven clinical infections were also analysed. RESULTS: A total of 107 earthquake-affected adults (58 females and 49 males, median [IQR] age: 37 [27-57] years) were analysed. Infection was present in 50.5% of the patients, predominantly with multidrug-resistant pathogens. Amputation (OR 5.30) and intermittent hemodialysis (OR 2.98) before ICU ...