Design, synthesis, anticancer activity and molecular docking of quinoline-based dihydrazone derivatives

作者：Jiaxing Lu, Hai-Rong Lan, Dai Zeng, Junying Song, Yating Hao, Ai‐Ping Xing, Ao Shen, Juan Yuan · 发表于：RSC Advances · 年份：2025 · DOI：10.1039/d4ra06954d · 被引用次数：20 · 研究领域：Cancer therapeutics and mechanisms、Cancer Mechanisms and Therapy、Synthesis and biological activity

partial insertion. Additionally, molecular docking also suggests that CDK2 may be one of the targets for 3b and 3c. In a word, 3b and 3c could be suitable candidates for further investigation as chemotherapeutic agents in cancer treatment.