Review of Applications of Microneedling in Melasma

作者：Wenwen Chen, Xingling Jian, Bo Yu · 发表于：Journal of Cosmetic Dermatology · 年份：2024 · DOI：10.1111/jocd.16707 · 被引用次数：8 · 研究领域：Dermatologic Treatments and Research、melanin and skin pigmentation、Laser Applications in Dentistry and Medicine

BACKGROUND: Melasma, a common skin pigmentation disease, can negatively impact patients' mental health, social interactions, and physical appearance. Although we now have several treatments accessible, such as medicines, chemical peels, and phototherapy, which can help ease symptoms to some extent, the requirement for a long-term effective and safe treatment for patients is far from met. In the face of this problem, microneedling, as an innovative treatment, provides a new avenue for treating melasma. Although microneedling has been extensively investigated for treating other skin issues such as inflammation, scarring, and photoaging, research into its use in melasma treatment is still in its early stages. OBJECTIVE: This study aimed to gather and assess clinical information on microneedling's effectiveness in treating melasma, covering research gaps and serving as a beneficial reference for clinical therapy. METHODS: We searched PubMed, Cochrane, Scopus, Embase, and Web of Science databases for articles with the keywords "microneedling," "percutaneous collagen induction", and "melasma." Following a thorough assessment, we selected 64 clinical studies that matched the requirements for in-depth analysis. RESULTS: After thoroughly reviewing these data, we concluded that microneedling has tremendous potential for treating melasma. Microneedling can significantly improve treatment outcomes, especially when paired with additional therapies such as topical medicines or phototherapy...