Advances in field effect transistor based electronic devices integrated with CMOS technology for biosensing

作者：Harshita Rai, Kshitij RB Singh, Arunadevi Natarajan, Shyam S. Pandey · 发表于：Talanta Open · 年份：2024 · DOI：10.1016/j.talo.2024.100394 · 被引用次数：28 · 研究领域：Analytical Chemistry and Sensors、Nanowire Synthesis and Applications、Analog and Mixed-Signal Circuit Design

• zCMOS technology in biosensing applications. • Emphasis on field effect transistor (FET)-based biosensors. • Highlights advancements in analytical and bioanalytical fields. • Addresses unique contributions and future perspectives in biosensor technology. • Overcoming challenged with molecularly imprinted polymers (MIPs). This review article embarks on an enlightening journey through the multifaceted realm of electronic devices and their applications in biosensing, emphasizing the role of Field effect transistor (FET) based biosensors and Complementary Metal Oxide Semiconductor (CMOS) processes in biosensing device development. It begins by elucidating the foundational principles of biosensing and underscoring the crucial contribution of transducers, establishing a robust understanding of the field. The article unravels the intricate interplay between electronic biosensors and CMOS processes, offering a concise yet insightful exploration of their operational intricacies, diverse practical applications, and recent advancements. Additionally, it spotlights the pivotal role of FET-based biosensors integrated with CMOS processes in miniaturizing biosensors and thus amplifying their real-world efficacy. Moreover, the role of modern technologies, such as the Internet of Things (IoT), in recent biosensor development has been discussed. By addressing inherent challenges like sensitivity, integration, cost, and accessibility, the article underscores the vital role of biosensing techn...