Is there a comparable Mp-MRI for incidental prostate uptake on 18 F-FDG PET/CT?

作者：Merve Şam Özdemir, Nurullah Kaya, Metin Savun, Emin Taha Keskin, Sabahattin Yüzkan, Fatma Zeynep Arslan, Burcu Budak, Özgür Omak, Aytül Hande Yardımcı, Harun Özdemir · 发表于：World Journal of Surgical Oncology · 年份：2024 · DOI：10.1186/s12957-024-03578-0 · 被引用次数：2 · 研究领域：Prostate Cancer Diagnosis and Treatment、Prostate Cancer Treatment and Research、MRI in cancer diagnosis

PURPOSE: Although 18 F-FDG-PET/CT is helpful in defining many types of cancer, localized prostate cancer should not be treated with this technique. This study describes the use of multi-parametric MRI (mpMRI) to characterize incidental 18 F-FDG uptake in the prostate. METHODS AND MATERIALS: While 18 F-FDG-PET/CT is useful for characterizing a variety of cancers, it is not advised for prostate cancer that is localized. This work investigates the use of mpMRI to describe incidental 18 F-FDG uptake in the prostate.mpMRI included T2-weighted (T2W), dynamic contrast enhancement (DCE), and apparent diffusion coefficient (ADC) sequences. Patients were classified according to PI-RADS (Prostate Imaging Reporting and Data System) version 2.1 by an experienced uroradiologist, and 18 F-FDG-PET was evaluated to determine whether the area of involvement on CT had a counterpart in mpMRI. A biopsy was performed on 30 of the 92 patients. These patients' maximum standardized uptake values (SUVmax) 6 < and ≥ 6, PS(PSA) density 0.15 < and ≥ 0.15, PSA level, uptake pattern (focal involvement/diffuse involvement), and PI-RADS scores were compared. P < .05 was considered statistically significant. Logistic regression was used to analyze PI-RADS score groups age, PSA, PSA density and SUVmax. RESULTS: In the study, 92 patients with incidental 18 F-FDG-PET/CT prostate uptake were examined. Median age was 66, PSA median was 3.6 ng/ml (range: 0-3198 ng/ml). Notably, in 70.6% of cases, PET/CT uptake didn...