Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application

作者：Mingyao Weng, Jiayue Wang, Yiran Liu, Simei Ou, Jinyi Xiang, Guanting Huang, Jingnan Xiong, Qiuyan Wu, Yuhan Zhou, Hao Zhou, Dan Wang · 发表于：Science of Traditional Chinese Medicine · 年份：2024 · DOI：10.1097/st9.0000000000000051 · 被引用次数：4 · 研究领域：Vagus Nerve Stimulation Research、Heart Rate Variability and Autonomic Control、Gastrointestinal motility and disorders

Abstract Functional gastrointestinal disorders (FGIDs) are debilitating diseases of the digestive system that severely impair an individual’s quality of life and impose a significant economic burden. However, the mechanisms underlying the pathogenesis of FGIDs and effective treatment options remain unclear. Transcutaneous auricular vagus nerve stimulation (taVNS), a novel neuromodulation therapy, has shown promising therapeutic outcomes in the treatment of FGIDs. This study conducted a comprehensive analysis of the development of taVNS and its relationship with vagus nerve stimulation and explored the clinical application of taVNS in managing FGIDs, including functional dyspepsia, irritable bowel syndrome, and functional constipation. Additionally, this study investigated the pathophysiological mechanisms of taVNS in FGIDs and reviewed its application as a holistic treatment approach, aiming to provide new insights into its therapeutic potential.