Prevalence of depression among women with polycystic ovary syndrome in mainland China: a systematic review and meta-analysis

作者：Zhenzhen Hong, Peiya Wu, Hong Zhuang, Liying Chen, Shanshan Hong, Jiawei Qin · 发表于：BMC Psychiatry · 年份：2024 · DOI：10.1186/s12888-024-06378-8 · 被引用次数：9 · 研究领域：Ovarian function and disorders、Maternal Mental Health During Pregnancy and Postpartum、Menstrual Health and Disorders

OBJECTIVE: Polycystic ovary syndrome (PCOS), a prevalent endocrine disorder among women, is frequently comorbid with depression. This systematic review and meta-analysis aimed to estimate the prevalence of depression among women with PCOS in mainland China. METHOD: A comprehensive literature search was conducted in PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, and Chinese databases (CNKI, WanFang, and VIP) up to August 2024. Random-effects models were applied to estimate the pooled prevalence of depression with 95% confidence intervals. The methodological quality assessment was assessed using the risk of bias tool. The primary outcome was the pooled prevalence of depression in women with PCOS. RESULTS: were 38% and 34%, respectively. The prevalence of depression among women with PCOS that used Self-rating Depression Scale (SDS), Patient Health Questionnaire-9 (PHQ-9), Beck Depression Inventory (BDI), and Hospital Anxiety and Depression Scale (HADS) were 40%, 34%, 31%, and 24%, respectively. Sensitivity analysis and meta-regression confirmed the stability of the findings. Evidence of publication bias was detected. CONCLUSIONS: The high prevalence of depression among women with PCOS in China underscores the need for integrated screening and management. The results of this meta-analysis show high heterogeneity and indicate publication bias, which reduces the generalizability of the findings. Future research should address heterogeneity and enhance the appli...