Epidemiology of pulmonary embolism in China, 2021: a nationwide hospital-based study

作者：Kaiyuan Zhen, Yuzhi Tao, Xia Lei, Shengfeng Wang, Qian Gao, Dingyi Wang, Zhaofei Chen, Xianglong Meng, Yuting Kang, Guohui Fan, Zhu Zhang, Peiran B Yang, Jixiang Liu, Yu Zhang, Chaozeng Si, Wei Wang, Jun Wan, Yuanhua Yang, Zhihong Liu, Yingqun Ji, Juhong Shi, Qun Yi, Guochao Shi, Yutao Guo, Nuofu Zhang, Zhaozhong Cheng, Ling Zhu, Zhe Cheng, Xianbo Zuo, Wanmu Xie, Qiang Huang, Shuai Zhang, Lanxia Gan, Bing Liu, Simiao Chen, Cunbo Jia, Chen Wang, Zhenguo Zhai · 发表于：The Lancet Regional Health - Western Pacific · 年份：2024 · DOI：10.1016/j.lanwpc.2024.101258 · 被引用次数：23 · 研究领域：Venous Thromboembolism Diagnosis and Management、Atrial Fibrillation Management and Outcomes、COVID-19 Clinical Research Studies

Background: Pulmonary embolism (PE) as a preventable and potentially fatal noncommunicable disease was believed to have a lower incidence in Asian populations compared to Western populations. However, the incidence and mortality rates of PE in China and the impact of venous thromboembolism (VTE) prevention system constructions on PE still lack nationwide evidence. Methods: For this nationwide hospital-based observational study, we used data from the National Hospital Quality Monitoring System (HQMS) and public database in China. We estimated the incidence and in-hospital mortality rates of PE by age group, sex, and regions of geographical and socioeconomic level. VTE prevention and management system constructions were quantified by geographical density. We then calculated the incidence and mortality rates in different conditions of VTE prevention and management system construction. Findings: During the 12 months period between January and December 2021, a total number of 200,112 PE patients and 14,123 deaths were recorded from 5101 hospitals in the HQMS database. The incidence of PE was 14.19 (200,112, 95% CI 14.13-14.26) per 100,000 population and the mortality rate was 1.00 (95% CI 0.99-1.02) per 100,000 population. The incidence of PE was higher in male patients (14.43 per 100,000 population) than in female patients (13.95 per 100,000 population). Disparities of incidence and mortality rates were shown within age groups and geographical regions. The incidence and mortality...