Side Effects of Psychotropic Medications Experienced by a Community Sample of People Living With Severe and Persistent Mental Illness

作者：Jack C. Collins, Amanda Wheeler, Sara S. McMillan, Jie Hu, Sarira El‐Den, Helena Roennfeldt, Claire L. O’Reilly · 发表于：Health Expectations · 年份：2024 · DOI：10.1111/hex.70122 · 被引用次数：13 · 研究领域：Schizophrenia research and treatment、Sleep and related disorders、Treatment of Major Depression

BACKGROUND: Psychotropic medications are a common treatment modality for people living with severe and persistent mental illness (SPMI). While effective in reducing relapse and hospitalisation, psychotropic medications cause numerous side effects, varying in nature and severity. Identification and management of side effects is crucial in the ongoing management of SPMI. OBJECTIVE: To characterise the side effects of psychotropic medications, experienced by a sample of consumers living with SPMI, using a validated tool. SETTING AND PARTICIPANTS: Consumers with SPMI living in the community were recruited from all 25 community pharmacies across four Australian regions, which were allocated to the intervention arm of the Bridging the Gap between Physical and Mental Illness (PharMIbridge) randomised controlled trial (RCT). MAIN OUTCOME MEASURES: Responses to the My Medicines & Me Questionnaire (M3Q). RESULTS: Consumers (n = 156) most frequently reported side effects in the categories of sleep-related side effects (80.8%, n = 126), mood-related side effects (75.6%, n = 118) and weight and appetite changes (60.3%, n = 107). Daytime somnolence was the most reported individual side effect (68.6%, n = 107). Mood-related side effects were ranked as the most bothersome, followed by sleep-related side effects and weight and appetite changes. More than one-quarter (29.5%, n = 46) of consumers reported choosing not to take their medications due to side effects. Consumers more frequently told...