Obstructive sleep apnea syndrome (OSAS) in women: A forgotten cardiovascular risk factor

作者：Federica Moscucci, Federica Moscucci, Valentina Bucciarelli, Sabina Gallina, Sabina Gallina, Susanna Sciomer, Susanna Sciomer, Anna Vittoria Mattioli, Anna Vittoria Mattioli, Silvia Maffei, Savina Nodari, Roberto Pedrinelli, P. Andreozzi, Stefania Basili, Stefania Basili, Sabina Gallina, Sabina Gallina, Federica Moscucci, Federica Moscucci, Anna Vittoria Mattioli, Anna Vittoria Mattioli, Susanna Sciomer, Susanna Sciomer, Valentina Bucciarelli, Fabrizio Ricci, F Angeli, Camilla Torlasco, Stefania Basili, Stefania Basili, C Becattini, Elena Buzzetti, Chiara Cogliati, Anna Licata, Alberto Marra, Maristella Masala, M.L. Muiesan, Salvatore Piano, M Proietti, Valeria Raparelli, Giulio Francesco Romiti, Giuseppina Russo, Francesca Santilli, Elena Succurro, Patrizia Suppressa · 发表于：Maturitas · 年份：2024 · DOI：10.1016/j.maturitas.2024.108170 · 被引用次数：22 · 研究领域：Obstructive Sleep Apnea Research、Neuroscience of respiration and sleep、Sleep and Wakefulness Research

Sleep-disordered breathing is a highly prevalent disorder with negative impact on healthcare systems worldwide. This condition has detrimental effects on cardiovascular health and quality of life, and is frequently associated with a variety of comorbidities, including cardiovascular disease, heart failure, diabetes and atrial fibrillation. Nevertheless, it remains frequently undiagnosed and undertreated, especially in specific populations. Studies on sleep-disordered breathing have been conducted mainly on male patients, and the prevalence and severity of this disorder in women are underestimated. Recently, some clinical and laboratory evidence has highlighted the epidemiological and pathophysiological differences between men and women with sleep-disordered breathing. In this review, we discuss sex-related mechanisms of sleep-disordered breathing in frequently associated disorders, to improve clinical understanding of this condition and to simplify the practical application of targeted interventions. The aim is to improve prognosis among female patients and guarantee a better quality of life and a reduction in healthcare costs.