BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate

作者：Selami Demirci, Jing Zeng, Rahul Palchaudhuri, Chuanfeng Wu, Diana M. Abraham, Taha Bartu Hayal, Khaled Essawi, My Anh Nguyen, Ulana Stasula, Rebecca Chu, Alexis Leonard, Shaina N. Porter, Muhammad Behroz Naeem Khan, Gabriela Hinojosa, Naoya Uchida, Sogun Hong, Cícera R. Lazzarotto, Nola Neri, Lucas Ferreira da Silva, Danilo Pellin, Archana Verma, Leanne Lanieri, Anjali Bhat, Katelyn J. Hammond, Tiffany Tate, Stacy A. Maitland, Fatemeh Sheikhsaran, Aylin Bonifacino, Allen E. Krouse, Nathaniel S. Linde, Theresa Engels, Justin Golomb, Shengdar Q. Tsai, Shondra M. Pruett‐Miller, David T. Scadden, Cynthia E. Dunbar, Scot A. Wolfe, Robert E. Donahue, Lisa Olson, Daniel E. Bauer, John F. Tisdale · 发表于：Cell stem cell · 年份：2024 · DOI：10.1016/j.stem.2024.10.014 · 被引用次数：17 · 研究领域：Erythrocyte Function and Pathophysiology、Blood groups and transfusion、Hemoglobinopathies and Related Disorders