FBLN7 mediates vascular smooth muscle cell phenotype switching and vascular remodeling in hypertension

作者：Guoqing Yao, Xuehui Zheng, Yang Hu, Yuan Zhao, Binghui Kong, Yun Ti, Pengli Bu · 发表于：Theranostics · 年份：2024 · DOI：10.7150/thno.102593 · 被引用次数：10 · 研究领域：Apelin-related biomedical research

These findings reveal FBLN7 promotes the transition of VSMCs from a contractile to a synthetic phenotype, thereby aggravating vascular remodeling. This provides further insights into the pathogenesis of vascular remodeling and potential therapeutic strategies.