One Health approach probes zoonotic non-typhoidal Salmonella infections in China: A systematic review and meta-analysis

作者：Jiaqi Chen, Linlin Huang, Hongli An, Zining Wang, Xiamei Kang, Rui Yin, Chenghao Jia, Xiuyan Jin, Min Yue · 发表于：Journal of Global Health · 年份：2024 · DOI：10.7189/jogh.14.04256 · 被引用次数：46 · 研究领域：Salmonella and Campylobacter epidemiology、Zoonotic diseases and public health、Animal Virus Infections Studies

Background: Zoonotic infections, particularly those caused by non-typhoidal Salmonella (NTS), pose a significant disease burden. However, there is a notable lack of comprehensive and integrated studies employing the One Health approach to address Salmonella prevalence. In this study, we aimed to analyse NTS spatiotemporal prevalence, serovar distribution, and antimicrobial resistance (AMR) across China. Methods: We conducted a systematic review and meta-analysis to understand the dynamics of NTS in a One Health context in China. We searched the CNKI, Wanfang, and PubMed databases for Chinese and English peer-reviewed articles published before 1 January 2022 dealing with Salmonella in the context of China. We examined the dynamic prevalence along the food chain, the risk of dominant serovars and the carriers' regional contribution by principal component analysis, and the AMR burden before and after the ban on using antimicrobials as feed additives across five decades. We used the inverse variance index as an indicator of the inconsistency across studies, and we adopted the restricted maximum likelihood model due to high heterogeneity for analysis with a 95% confidence level for the pooled prevalence estimate. Results: Based on 562 retrieved high-quality studies during 1967-2021, representing 5 052 496 samples overall and 80 536 positive samples for NTS isolates, the overall average prevalence was 7.35% (95% confidence interval (CI) = 0.069-0.087), which was regionally relative...