Effects of high dietary carbohydrate intake in patients with obstructive sleep apnea

作者：Ying Shi, Jun Xu, Stephanie G. Yi, Chenyu Xu, Fei Yu, Wei Gu, Jing Zhang, Ye Liang · 发表于：Sleep And Breathing · 年份：2024 · DOI：10.1007/s11325-024-03188-w · 被引用次数：3 · 研究领域：Obstructive Sleep Apnea Research、Sleep and related disorders、Nutrition and Health in Aging

BACKGROUND: This study aimed to characterize the relationship between habitual food intake and OSA. METHODS: The diet of 200 volunteers was evaluated using a Food Frequency Questionnaire. The patients were further allocated to mild, moderate, and severe OSA groups. The relationships of OSA with diet were evaluated using multivariate linear regression analysis and the relationships of the energy supply ratio for three major nutrients and demand with sleep parameters were assessed using correlation analysis. RESULTS: The analysis of nutrient intake showed a reduced energy intake in non-OSA patients (11953.98 ± 7578.11 kJ, 95% CI 9677.27-14230.70 kJ) as compared to severe-OSA patients (15153.43 ± 6541.89 kJ, 95% CI 13678.46-16628.40 kJ) (p < 0.05). Similarly, lower intake of carbohydrates was observed in non-OSA (249.94 ± 134.96 g/day, 95% CI 209.39-290.48 g/day) as compared to severe OSA patients (348.57 ± 112.34 g/day, 95% CI 323.24-373.90 g/day) (p < 0.05). Compared with participants without OSA, we found that those with OSA had significantly poorer diets, with higher contents of rice (β = 0.195, p = 0.006), wheat (β = 0.236, p = 0.001), stuffed food items (β = 0.278, p < 0.001), fried food (β = 0.193, p = 0.006), dairy products (β = 0.198, p = 0.005), and sweet beverages (β = 0.154, p = 0.030). After adjustment for age, sex, the presence of diabetes, and waist-hip ratio, these relationships remained. Furthermore, a higher proportion of energy intake in the form of carbohydra...