3D Diffusion-Prepared FLASH for Prostate MRI Near Metallic Implants

作者：Jeremiah Hess, Philip Lee, Andrew A. Gomella, Andreas M. Loening, Brian Hargreaves · 发表于：Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · 年份：2024 · DOI：10.58530/2024/4758 · 被引用次数：1 · 研究领域：Advanced MRI Techniques and Applications、Additive Manufacturing Materials and Processes、Advanced X-ray and CT Imaging

Motivation: Diffusion weighted imaging (DWI) is critical for prostate MRI, but echo planar imaging (EPI) DWI suffers from severe distortion in patients with hip implants or excessive bowel gas, often rendering images unusable. Goal(s): To develop 3D DWI of the prostate with minimal distortion from nearby metal. Approach: We compared a diffusion prepared, phase-navigated, fast low-angle shot (FLASH) readout sequence to EPI DWI to assess image quality, distortion correction and diffusion contrast. Results: Phantom experiments demonstrate the reduced FOV, distortion correction and ADC accuracy. Images in human subjects avoid the severe signal loss and distortion of EPI DWI in the subject with metal. Impact: We showed that 3D diffusion-prepared FLASH enables DWI where EPI often fails near hip replacements. Increased robustness of prostate imaging protocols to the presence of metal and/or bowel gas may obviate the need for contrast injection in these patients.