Gut microbiota-derived tryptophan metabolites regulated by Wuji Wan to attenuate colitis through AhR signaling activation

作者：Wanghui Jing, Sijing Dong, Yinyue Xu, Jingjing Liu, Jiawei Ren, Xue Liu, Min Zhu, M Zhang, Hehe Shi, Na Li, Peng Xia, Haitao Lu, Sicen Wang · 发表于：Acta Pharmaceutica Sinica B · 年份：2024 · DOI：10.1016/j.apsb.2024.11.009 · 被引用次数：64 · 研究领域：Gut microbiota and health、Pharmacological Effects of Natural Compounds、Gastrointestinal motility and disorders

-IAA-AhR signaling pathway. This study provides novel insights into colitis pathogenesis and presents an effective therapeutic and preventive approach against IBD.