Bioactive matters based on natural product for cardiovascular diseases

作者：Linfang Zhong, Xiaoying Tan, Wenhui Yang, Peishan Li, Lianbao Ye, Qi Luo, Honghao Hou · 发表于：Smart Materials in Medicine · 年份：2024 · DOI：10.1016/j.smaim.2024.11.001 · 被引用次数：10 · 研究领域：Pharmacological Effects of Natural Compounds、Natural product bioactivities and synthesis、Medicinal Plants and Bioactive Compounds

Natural products are valuable sources of bioactive compounds for drug development. It is useful to explore natural products to treat cardiovascular disease. This review provides an overview of the natural products, including their general sources, structure types, functional methods, applications for cardiovascular diseases and future challenges. We highlight recent advances in drug delivery systems of natural products applicated in cardiovascular diseases such as nanoparticles, microspheres and hydrogels, and outline general strategies for functionalizing the natural product with various biological. Finally, we propose our perspective on challenges and future developments in this rapidly-evolving field. • This manuscript summaries the general sources, structure types and functionality methods of natural products, especially in cardiovascular diseases. • This review highlights recent advances in drug delivery systems of natural products applicated in cardiovascular diseases such as nanoparticles, microspheres and hydrogels. • This review proposes the key challenges and prospects of natural products applicated for cardiovascular diseases.