Perioperative outcomes and hospitalization costs of radical vs. conservative surgery for hepatic cystic echinococcosis: A retrospective study

作者：Honggang Shi, Kahaer Tuerxun, Aizizaimu Yusupu, Zainuer Yusupu, Qi‐Lin Xu, Yibin Jia, Musitaba Maimaitireyimu, Tuerhongaji Maimaitiaili, Muzaipaer Muhetajiang, Jiaxin Lin, Chengmin Ma, Xiaofeng Li, Yuanquan Wu, Yonghui Su · 发表于：PLoS neglected tropical diseases · 年份：2024 · DOI：10.1371/journal.pntd.0012620 · 被引用次数：6 · 研究领域：Parasitic infections in humans and animals、Amoebic Infections and Treatments、Ureteral procedures and complications

BACKGROUND: Surgical intervention is a crucial treatment for hepatic cystic echinococcosis. However, the choice between radical and conservative surgery remains controversial. This study aimed to compare the perioperative outcomes and hospitalization costs between radical and conservative surgery for hepatic cystic echinococcosis. METHOD: A retrospective cohort study was conducted on patients undergoing surgical treatment at the First People's Hospital of Kashi Prefecture from July 1, 2012, to October 1, 2023. Propensity score-matching analysis was utilized to mitigate patient selection bias between the two surgical groups. RESULT: Of the 434 patients included, 324 underwent conservative surgery and 110 underwent radical surgery. After propensity score-matching, 182 conservative surgery and 102 radical surgery patients were compared. Radical surgery patients experienced longer operative time, higher intraoperative blood loss, increased blood transfusion, and higher costs compared to conservative surgery patients. However, no differences were observed in short-term outcomes, including overall morbidity, death, bile leak, effusion, pulmonary infection, incision infection, intestinal obstruction, ICU stay, abdominal drainage time, and postoperative hospital stays. CONCLUSION: This study suggests that radical surgery is associated with greater surgical complexity and higher hospitalization costs, while it doesn't offer a significant short-term advantage. Conservative surgery may ...