Global Incidence and Prevalence of Chronic Rhinosinusitis: A Systematic Review

作者：Hye Kyu Min, Sooji Lee, Soeun Kim, Yejun Son, Jaeyu Park, Hyeon Jin Kim, Jinseok Lee, Hayeon Lee, Lee H. Smith, Masoud Rahmati, Jiseung Kang, Nikolaos G. Papadopoulos, Seong Cho, Jong Woo Hahn, Dong Keon Yon · 发表于：Clinical & Experimental Allergy · 年份：2024 · DOI：10.1111/cea.14592 · 被引用次数：91 · 研究领域：Sinusitis and nasal conditions、Olfactory and Sensory Function Studies、Allergic Rhinitis and Sensitization

OBJECTIVE: Data on the global prevalence of chronic rhinosinusitis (CRS) is significantly varied and limited across countries and over time. Therefore, we aimed to conduct a comprehensive investigation into the global, regional, and national burden of CRS from the years 1980 to 2021, as well as identify those factors that influence levels of such burden. DESIGN: We conducted a systematic review and meta-analysis of general population-based observational studies focusing on CRS. We calculated pooled estimates of CRS prevalence and incidence with 95% confidence intervals (CIs). Subgroup analyses were conducted stratifying by sex, age cohorts, geographic regions, smoking status, obesity, and comorbid conditions. DATA SOURCES: PubMed/MEDLINE, EMBASE, CINAHL, Google Scholar, and Cochrane databases. ELIGIBILITY CRITERIA FOR SELECTION: We included general population-based observational studies on CRS published from database inception through October 20, 2023. RESULTS: A total of 28 eligible studies, encompassing more than 237 million participants and 11,342,923 patients with CRS from 20 countries across four continents, were included in the analysis. Global pooled prevalence of CRS and CRS with nasal polyps (CRSwNP) was found to be 8.71% (95% CI, 6.69-11.33; number of studies, 20) and 0.65% (95% CI, 0.56-0.75; number of studies, 4), respectively. The prevalence of CRS was greater in Europe compared with North America, South America, and Asia; adults compared with children; smokers c...