EtOH-mediated cascade C(sp 3 )–H alkylation via aromatization-driven [1,6]-hydride transfer: green and divergent synthesis of spirocyclic azepino[4,3,2- cd ]indoles

作者：Yao‐Bin Shen, Qian-Hao Zhuang, Xiao-Lin Wang, Xiao‐De An, Bin Qiu, Tiesheng Shi, Jian Xiao · 发表于：Green Chemistry · 年份：2024 · DOI：10.1039/d4gc04534c · 被引用次数：38 · 研究领域：Catalytic C–H Functionalization Methods、Oxidative Organic Chemistry Reactions、Asymmetric Hydrogenation and Catalysis

Unprecedented EtOH-mediated cascade C(sp 3 )–H alkylation reactions of 4-dialkylamino-indole-3-carbaldehydes have been realized for the green and divergent synthesis of spirocyclic azepino[4,3,2- cd ]indole derivatives.