An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy

作者：Braxton L. Jamison, Matthew Lawrance, Chun Jing Wang, Hannah A. DeBerg, Lauren Ziegler, David M. Sansom, Marc A. Gavin, Lucy S. K. Walker, Daniel Campbell · 发表于：Cell Reports · 年份：2024 · DOI：10.1016/j.celrep.2024.114938 · 被引用次数：21 · 研究领域：T-cell and B-cell Immunology、Immunotherapy and Immune Responses、Immune Cell Function and Interaction

cells have enhanced functional properties and restrict cDC function, offering promise for targeted immunotherapy use in autoimmune disease.