Advancement in Multi-omics approaches for Uterine Sarcoma

作者：Wuyang Wang, Yu Hu, Fangfang Fu, Wu Ren, Tian Wang, Shixuan Wang, Yan Li · 发表于：Biomarker Research · 年份：2024 · DOI：10.1186/s40364-024-00673-y · 被引用次数：7 · 研究领域：Cancer Genomics and Diagnostics、Sarcoma Diagnosis and Treatment、Cancer Cells and Metastasis

Uterine sarcoma (US) is a rare malignant tumor that has various pathological types and high heterogeneity in the female reproductive system. Its subtle early symptoms, frequent recurrence, and resistance to radiation and chemotherapy make the prognosis for US patients very poor. Therefore, understanding the molecular mechanisms underlying tumorigenesis and progression is essential for an accurate diagnosis and targeted therapy to improve patient outcomes. Recent advancements in high-throughput molecular sequencing have allowed for a deeper understanding of diseases through multi-omics technologies. In this review, the latest progress and future potential of multi-omics technologies in US research is examined, and their roles in biomarker discovery and their application in the precise diagnosis and treatment of US are highlighted.