Recurrence and postoperative quality of life after surgical resection of unilateral cT1–T3N1bM0 papillary thyroid carcinoma

作者：Zhilin Qiu, Liang Zhang, Xi Guo, Zhaoming Ding, Jihua Han, Wen Bi, Bing Sun, Jiewu Zhang, Chunlei Nie · 发表于：Gland Surgery · 年份：2024 · DOI：10.21037/gs-24-178 · 被引用次数：6 · 研究领域：Thyroid and Parathyroid Surgery、Thyroid Cancer Diagnosis and Treatment、Multiple and Secondary Primary Cancers

Background: Determining the optimal extent of surgery and improving postoperative quality of life for patients with papillary thyroid cancer has been an important challenge. Here, we evaluated postoperative quality of life after cT1–T3N1bM0 papillary thyroid carcinoma (PTC) to explore the optimal scope of surgical resection. Methods: In this study, we investigated surgical outcomes in patients diagnosed with unilateral cT1–T3N1bM0 PTC, who were treated at Harbin Medical University Cancer Hospital from January 2008 to December 2018. To achieve this, we divided the patients into two distinct groups based on the extent of surgery they received: the non-total thyroidectomy group (group A) and the total thyroidectomy group (group B). To comprehensively evaluate the patients’ well-being, we assessed their psychological status, disease recurrence rate, postoperative complications, and quality of life. Results: A total of 362 patients diagnosed with thyroid cancer were included in this study, with group A (n=88) and group B (n=274) classified based on the extent of surgery received. Significant differences were observed between the two groups in terms of clinical and pathological characteristics, including age (χ2=10.962, P=0.001), sex (χ2=5.906, P=0.02), multifocal (χ2=5.515, P=0.02), contralateral glandular nodule (χ2=34.616, P<0.001), clinical Tumor, Node, Metastasis (TNM) stage (χ2=11.340, P=0.001), and complication rate (χ2=4.265, P=0.04). Notably, group B exhibited higher rates...