TRIM4 enhances small-molecule-induced neddylated-degradation of CORO1A for triple negative breast cancer therapy

作者：Wenjie Gu, Xiaoxia Liu, Yiwen Shen, Yi-Ting Gong, Yili Chen, Jiayi Lin, Dong Lu, Li-Jun Zhang, Hongzhuan Chen, Yi Jin, Zha‐Jun Zhan, Weidong Zhang, Jinmei Jin, Xin Luan · 发表于：Theranostics · 年份：2024 · DOI：10.7150/thno.97662 · 被引用次数：11 · 研究领域：interferon and immune responses、Peptidase Inhibition and Analysis、Galectins and Cancer Biology

Our findings underscore the critical role of CORO1A in TNBC and lay a crucial foundation for the development of innovative drugs based on molecular glue technology.