BATF2 inhibits the stem cell-like properties and chemoresistance of gastric cancer cells through PTEN/AKT/β-catenin pathway

作者：Long‐Long Cao, Kai Weng, Lujie Li, Guang‐Tan Lin, Yuxuan Zhao, Youxin Gao, Xiaobo Huang, Qiyue Chen, Jiabin Wang, Chao‐Hui Zheng, Chang‐Ming Huang, Jian-Wei Xie, Ping Li · 发表于：Theranostics · 年份：2024 · DOI：10.7150/thno.98389 · 被引用次数：21 · 研究领域：Cancer-related molecular mechanisms research、Cholangiocarcinoma and Gallbladder Cancer Studies

BATF2 plays a pivotal role in regulating stem-like characteristics and chemoresistance in gastric cancer through the BATF2/PTEN/AKT/ABCG2 pathway. These findings suggest a novel therapeutic strategy targeting BATF2 to enhance chemotherapy effectiveness in gastric cancer treatment.