Wildfire-sourced fine particulate matter and preterm birth risks in Brazil: A nationwide population-based cohort study

作者：Yiwen Zhang, Wenzhong Huang, Rongbin Xu, Tingting Ye, Gongbo Chen, Xu Yue, Micheline de Sousa Zanotti Stagliorio Coêl, Paulo Hilário Nascimento Saldiva, Jiangning Song, Yuming Guo, Shanshan Li · 发表于：Journal of Hazardous Materials · 年份：2024 · DOI：10.1016/j.jhazmat.2024.136290 · 被引用次数：11 · 研究领域：Air Quality and Health Impacts、Energy and Environment Impacts、Toxic Organic Pollutants Impact

Wildfire-specific particulate matter with diameters ≤ 2.5 µm (PM 2.5 ) is the key component of wildfire smoke, with potentially higher toxicity than PM 2.5 from other sources. In this nationwide population-based cohort study, we included 22,163,195 births from Brazil during 2010 2019. Daily wildfire-specific PM 2.5 was estimated through the chemical transport model. Time-varying Cox proportional hazards models were used to characterize the exposure-time-response (E-T-R) relationship between weekly wildfire-specific PM 2.5 exposure and preterm birth (PTB) risks, followed by subgroup analyses. A 10 µg/m 3 increment in wildfire-specific PM 2.5 was associated with a hazard ratio of 1.047 (95 % confidence interval [CI]: 1.032–1.063) for PTB. Stronger associations between wildfire-specific PM 2.5 and PTB were observed during earlier pregnancy, among female infants, and pregnant women < 18 years old, in ethnic minorities, with a length of education ≥ 11 years, from low-income or high-temperature municipalities, and residing in North/Northeast regions. An estimated 1.47 % (95 % CI: 1.01 % 1.94 %) of PTBs were attributable to wildfire-specific PM 2.5 in Brazil, increasing from 2010 to 2019. The PTBs attributable to wildfire-specific PM 2.5 surpassed those attributed to non-wildfire PM 2.5 (0.31 %, 95 % CI: 0.09 % 0.57 %). Wildfire emerged as a critical source contributing to the PM 2.5 -linked PTBs. Prioritized fire management and emission control strategies are warranted for PTB prev...