Current research status of Raman spectroscopy in glioma detection

作者：Jie Liu, Pan Wang, Hua Zhang, Yuansen Guo, Mingjie Tang, Junwei Wang, Nan Wu · 发表于：Photodiagnosis and Photodynamic Therapy · 年份：2024 · DOI：10.1016/j.pdpdt.2024.104388 · 被引用次数：8 · 研究领域：Spectroscopy Techniques in Biomedical and Chemical Research、Optical Imaging and Spectroscopy Techniques、Nanoplatforms for cancer theranostics

• Raman spectroscopy enables a rapid, accurate, and label-free approach to glioma detection. • Introduced the applications of Raman spectroscopy in glioma identification and classification. • Discussed the main challenges in the clinical application of Raman spectroscopy. • The article could provide some references for the further development of Raman spectroscopy in glioma diagnosis. Glioma is the most common primary tumor of the nervous system. Conventional diagnostic methods for glioma often involve time-consuming or reliance on externally introduced materials. Consequently, there is an urgent need for rapid and reliable diagnostic techniques. Raman spectroscopy has emerged as a promising tool, offering rapid, accurate, and label-free analysis with high sensitivity and specificity in biomedical applications. In this review, the fundamental principles of Raman spectroscopy have been introduced, and then the progress of applying Raman spectroscopy in biomedical studies has been summarized, including the identification and typing of glioma. The challenges encountered in the clinical application of Raman spectroscopy for glioma have been discussed, and the prospects have also been envisioned.