Myocardial Abnormalities Across the AHA/ACC Stages of Heart Failure in Patients With Diabetes

作者：Wenjing Yang, Leyi Zhu, Weichun Wu, Mengdi Jiang, Huaying Zhang, Di Zhou, Jing Xu, Yining Wang, Qiang Zhang, Arlene Sirajuddin, Andrew E. Arai, Shihua Zhao, Minjie Lu · 发表于：JACC Asia · 年份：2024 · DOI：10.1016/j.jacasi.2024.08.016 · 被引用次数：5 · 研究领域：Cardiovascular Function and Risk Factors、Cardiac Imaging and Diagnostics、Cardiovascular Disease and Adiposity

Background: Cardiac magnetic resonance imaging (CMR) could serve as a robust tool for comprehensive evaluation of early changes across heart failure (HF) stages classified by the American Heart Association/American College of Cardiology guideline in diabetes mellitus (DM). Objectives: The authors aimed to explore phenotypic imaging features characterizing DM participants at different HF stages by CMR. Methods: DM participants with preserved ejection fraction who underwent CMR examination between January 2020 and December 2021 were evaluated. Left ventricular strain analysis and myocardial fibrosis was evaluated by CMR. Results: 0.05). Conclusions: Subclinical dysfunction and myocardial fibrosis derived from CMR were progressively remarkable with advancing HF stage in DM. Comprehensive CMR provided sensitive tools for better delineation of DM patients with pre-HF and at risk for HF.