Development and validation of a functional ability index for older adults: a multicohort study

作者：Yi Chang, Suman Sapkota, Bipin Thapa, Lina Ma, Linghui Sheng, Chaodong Wang, Jagadish K. Chhetri, Piu Chan · 发表于：Age and Ageing · 年份：2024 · DOI：10.1093/ageing/afae231 · 被引用次数：6 · 研究领域：Frailty in Older Adults、Nutrition and Health in Aging、Health disparities and outcomes

BACKGROUND: The aim of this study was to develop and validate a functional ability index (FAI) that incorporates aspects of intrinsic capacity and environmental factors of older individuals based on the World Health Organization framework of healthy ageing. METHODS: Data of 7016 participants ≥60 years participating in the baseline survey of China Health and Retirement Longitudinal Study was used for the development and internal validation of the FAI. External validation was performed in a separate cohort of 1295 older individuals aged ≥60 years. Functional independency was considered the primary outcome and additional proxies of healthy ageing were considered as secondary outcomes. Cluster dendrogram was used to identify the distinct hierarchical clusters of all included variables for inclusion in the FAI. Backward elimination logistic regression model was implemented to identify the most significant variables associated with independency to be included in the FAI. RESULTS: The FAI score ranged from 0 to 19 and individuals having FAI ≥ 12 were more likely to be independent and at lower risk of negative outcomes. For each unit increase in the FAI the risk of having independency increased by 30%-58% cross-sectionally in the two cohorts, whilst the 2-year risk of independency increased by 20%. The FAI demonstrated a C-statistic of 0.73 (95% confidence interval, 0.72 and 0.75) for the primary outcome. CONCLUSIONS: The FAI we developed effectively measured the functional ability s...