Clinical features of chronic tibial osteomyelitis: a single-center retrospective study of 282 cases in Xinjiang, China

作者：Xiaoxia Huang, Q. X. Li, Jiahan Chen, Tao Liu, Yan Zhao, Yong Teng · 发表于：BMC Musculoskeletal Disorders · 年份：2024 · DOI：10.1186/s12891-024-07928-7 · 被引用次数：3 · 研究领域：Orthopedic Infections and Treatments、Osteomyelitis and Bone Disorders Research、Diabetic Foot Ulcer Assessment and Management

BACKGROUND: Chronic osteomyelitis is a highly prevalent and severe orthopaedic complication, representing a critical unresolved issue. The clinical symptoms of osteomyelitis are influenced by various factors, including geography, lifestyle, and pre-existing medical conditions.This study aims to provide theoretical basis for treatment and prevention of osteomyelitis by investigating and analyzing clinical features and pathogen distribution among 282 patients with chronic tibial osteomyelitis in xinjiang. METHODS: A total of 282 patients with chronic tibial osteomyelitis from January 1, 2012 to January 1, 2022 in the First Affiliated Hospital of Xinjiang Medical University were retrospectively analyzed. All data were collected from electronic medical record (EMR) system including demographics, etiology, risk factors, osteomyelitis location and clinical classification. RESULTS: Farmers, students, unemployed and retirees accounted for a relatively large proportion of the 282 patients. There were 233 males and 49 females with a gender ratio of 4.75:1. The average age was 40.21 ± 15.68 years and was mainly concentrated in 41-50 years, specifically, the mean age of females was slightly older than that of males. Education level was mostly primary and secondary school education, and illiteracy. Risk factors of chronic tibial osteomyelitis included history of smoking and drinking, history of multiple repeated surgeries, and impaired immunity. Frequent clinical symptoms were in the orde...