Macrophage membrane‒biomimetic nanoparticles target inflammatory microenvironment for epilepsy treatment

作者：Chao Geng, Xing‐Hui Ren, Peipei Cao, Xiaoqi Chu, Penghu Wei, Quanlei Liu, Yongchang Lu, Bin Fu, Wen‐You Li, Yuhao Li, Guoguang Zhao · 发表于：Theranostics · 年份：2024 · DOI：10.7150/thno.99260 · 被引用次数：45 · 研究领域：Nanoparticle-Based Drug Delivery、RNA Interference and Gene Delivery、MicroRNA in disease regulation

MA@RT-HMSNs target inflammatory foci to inhibit death-related protein kinase 1 and exert antiepileptic effects. This study provides a promising biomimetic nanodelivery system for targeted epilepsy therapy.